(Renowned Chinese respiratory specialist Zhong Nanshan speaks at a press conference in Guangzhou, south China’s Guangdong Province, Feb. 18, 2020.
Renowned Chinese respiratory specialist Zhong Nanshan highlighted the studies on traditional Chinese medicines (TCM) in the fight against novel coronavirus disease (COVID-19). Speaking at a press conference held in Guangzhou, south China’s Guangdong Province, Zhong said the herbal prescription called “Pneumonia No. 1″ applied on Jan. 23 had proved effective in the treatment of COVID-19 patients in the province. According to Zhong, researchers are testing on the already widely used TCM drugs, such as Liushenwan and Lianhuaqingwen, to find out whether they can kill the virus, reduce the virus’ access to the cell and lower the incidence of a cytokine storm, meaning the massive inflammation which may lead to death. These tests may provide some evidence for the application of the TCM during the early and middle stages of the COVID-19, he said. TCM has never missed a single fight against epidemics throughout Chinese history. TCM classics have provided sufficient evidence of how TCM cured epidemic diseases such as smallpox over the past several thousand years.
TCT plays more and more important role in fighting against virus. The storage of medicine herbs calls for high requirement of temperature and humidity. Humidity is often associated with frizzy hair and headaches, but varying humidity levels can have more serious consequences on lifesaving drugs. While there are a lot of moving parts that go into producing medications, maintaining safety and potency through climate control is a responsibility that lies within the pharmaceutical industry.
By controlling humidity, costs can be lowered, and bottom lines increased without sacrificing quality. However, the quality and safety of a product are not up for debate. Strict regulations have been put in place by the World Health Organization (WHO) to protect public health on a global scale.
The World Health Organization recommends maintaining relative humidity levels around 50 percent. If levels climb above or dip below 50 percent, there can be detrimental effects on the quality, yield and shelf-life of the product.
Effects of Low Humidity
Static buildup is a major effect of relative humidity levels dropping below 45 percent. The accumulation of static charges can dry out medications, affecting the intended behavior of any solvents used in production. The excess static can also cause products to dry out and crumble, or stick together, leading to problems during tablet pressing and packaging.
Effects of High Humidity
High humidity causes products to absorb the excess moisture in the air, which can be just as destructive as environments with low humidity. Too much humidity can compromise potency and effectiveness, leading to degradation or even toxicity in some products. The potential for danger comes when relative humidity levels reach 60 percent or more; giving viruses, bacteria, mold, fungi and mites the opportunity to grow.
An overabundance of moisture can also affect production. When products absorb extra moisture, it causes them to either crumble or become sticky, which could clog machinery and bring production to a sudden halt.Optimal Storage Conditions
Temperature and humidity exposure are the primary factors that could cause products to become ineffective. Although facilities must tailor conditions around their product, the typical storage conditions for pharmaceuticals at room temperature should be kept between 15 °C and 25 °C (59 °-77 °F) with relative humidity levels around 50 percent.
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Post time: Mar-23-2020